The Science of Hiccups: Why Do We Hiccup?

Hiccups are a universal human experience that often strikes at the most inconvenient times. They can be irritating, amusing, and sometimes even a little alarming if they persist. Despite their ubiquity, many people don't understand why we hiccup or what purpose this strange bodily function serves.

In this article, we delve into the science of hiccups, exploring their causes, possible evolutionary purpose, and the latest research into how to stop them.

The Mechanics of a Hiccup

Before delving into why we hiccup, it's essential to understand what a hiccup is in terms of body mechanics. Hiccups, also known as singultus, are involuntary contractions (spasms) of the diaphragm, the muscle that separates the chest from the abdomen and plays a crucial role in breathing.

When the diaphragm contracts, it causes you to take a quick breath in. Immediately after the contraction, the larynx (or voice box) closes the glottis — the part of the larynx that contains the vocal cords. This closure happens so swiftly that it interrupts the breath, leading to the characteristic 'hic' sound of a hiccup.

But what triggers the diaphragm to contract irregularly? This leads us to the next section of our exploration.

Triggers and Causes of Hiccups

Hiccups are often associated with certain triggers, which can vary from person to person. Some common triggers include eating too quickly, consuming large quantities of food or drink, sudden changes in stomach temperature (for instance, when you drink a hot beverage followed by a cold one), alcohol, and fizzy drinks. Emotional stress or excitement can also prompt a bout of hiccups.

However, the exact cause of hiccups isn't fully understood, and they can sometimes appear seemingly out of nowhere. From a biological perspective, hiccups are controlled by the hiccup reflex arc, a neural circuit that includes parts of the medulla, phrenic nerves, and the diaphragm. Disruption to this circuit can lead to hiccups. Certain medical conditions, such as gastrointestinal disorders, neurological disorders, or even some medications, can interfere with this circuit and cause chronic hiccups.

The Evolutionary Purpose of Hiccups

Interestingly, hiccups are not exclusive to humans. Many mammals experience them, and hiccup-like movements are even observed in utero, leading scientists to believe that hiccups might have an evolutionary purpose.

One theory posits that the hiccup reflex might be a remnant from our amphibian ancestors. The rhythmic contractions characteristic of hiccups could be an adaptation for gill-breathing, which was performed by tadpole-like creatures hundreds of millions of years ago. The action of hiccupping might have helped these creatures to push water across their gills while keeping their mouths closed to avoid swallowing water.

Another theory suggests that hiccups might have served a purpose in mammalian infants' feeding. Specifically, hiccups might help to stimulate the suckling reflex or enable babies to coordinate their breathing and swallowing, preventing milk from entering their lungs.

Recent Research and Remedies for Hiccups

Despite hiccups being a common and usually harmless phenomenon, persistent or chronic hiccups can significantly impact an individual's quality of life and might indicate an underlying health problem. Recent research has focused on finding effective remedies for hiccups.

Some traditional hiccup-stopping techniques involve stimulating or irritating the pharynx, such as swallowing granulated sugar, sucking a lemon, or eating a spoonful of peanut butter. Other methods aim to increase carbon dioxide levels in the blood, like holding one's breath or breathing into a paper bag.

As for pharmaceutical interventions, certain medications have shown some efficacy in treating chronic cases, although the evidence is generally weak. Newer treatments under investigation include vagal nerve stimulation and phrenic nerve blocking.

In 2020, a device called the Forced Inspiratory Suction and Swallow Tool (FISST) was developed, which essentially is a rigid drinking straw that forces the user to use more suction than a typical straw, followed by a swallow. A small study found that this device could stop hiccups in nearly 92% of cases.

As we see, hiccups are a curious biological phenomenon that might hold traces of our evolutionary history. While often just an annoyance, persistent hiccups can also indicate health issues and have sparked innovative research into their treatment. Despite their simplicity, these tiny 'hics' carry a complexity that continues to puzzle and fascinate scientists.