Hoboken, N.J-February 18, 2025-The Wiley Foundation is pleased to announce that the 23rd annual Wiley Prize in Biomedical Sciences will be awarded to Iva Greenwald and Spyros Artavanis-Tsakonas for discovering the genes and novel biochemical mechanism of Notch signaling, which controls myriad cell fate decisions in metazoans.
Iva Greenwald is the Da Costa Professor of Biology in the Department of Biological Sciences and Professor of Biochemistry and Molecular Biophysics at Columbia University. Spyros Artavanis-Tsakonas is Professor Emeritus of Cell Biology at the Harvard Medical School, the Founding Director of the Developmental and Regenerative Biology Program at Harvard, and Professor Emeritus of Developmental Genetics at the Collège de France.
"Notch signaling involves unique biochemical steps and is used by animals to allow one cell to determine the fate of its neighbors. The Wiley Jury recognizes this important signaling pathway for its distinctive features and its critical role in human health and disease," said Dr. Titia de Lange of Rockefeller University, Chairperson of the Wiley Prize awards jury.
"The Wiley Foundation honors scientists who are dedicated to solving complex biological mechanisms which result in seminal discoveries that open the door for future innovations," said Deborah Wiley, Chair of the Wiley Foundation. "The work of the 23rd Annual Wiley Prize recipients truly upholds this mission by laying the foundation for core genetic and regulatory framework of the Notch signaling system, which unravels the fundamentals of normal and disease development and has fueled research into medicine for new treatments."
First awarded in 2002, the Wiley Prize in Biomedical Sciences is presented annually to recognize contributions that have opened new fields of research or have advanced concepts in a particular biomedical discipline. Among the many distinguished recipients of the Wiley Prize in Biomedical Sciences, thirteen have gone on to be awarded the Nobel Prize in Physiology or Medicine and five have been awarded the Nobel Prize in Chemistry.
This year's award will be presented to the winners at the Wiley Prize lecture, delivered as part of The Rockefeller University Lecture Series at 2:45 pm EDT on April 18, 2025. A recording of the Wiley Prize Lecture will be available at the Wiley Foundation website.
