Adolescent Brain Morphology and Gender Diversity

JAMA Network

About The Study: The findings of this study of 2,165 adolescents from the Netherlands general population suggest that global brain volumetric measures did not differ between adolescents who reported gender diversity and those who did not. However, these findings further suggest that gender diversity in the general population correlates with specific brain morphologic features in the inferior temporal gyrus among youths who are assigned male at birth. Replication of these findings is necessary to elucidate the potential neurobiological basis of gender diversity in the general population.

Authors: Akhgar Ghassabian, M.D., Ph.D., of the New York University Grossman School of Medicine in New York, is the corresponding author.

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(doi:10.1001/jamanetworkopen.2023.13139)

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