Aging Insight Goes Beyond Counting Birthdays

Pennsylvania State University

People's bodies can be old or young for their chronological age, depending, in part, on the amount and types of stressors they have experienced. Scientists can estimate people's biological age, but whether they use oral tissue or blood to make the measurement matters, according to a new study led by researchers in the Penn State Department of Biobehavioral Health.

Biological age - a measure of how well one's body is functioning - differs from chronological age - the amount of time since someone was born. While chronological age can be correlated to disease risk, researchers and medical doctors can use biological age, which can be slowed or accelerated by environmental or behavioral factors, to more precisely understand a person's risk for certain diseases, including cancers and dementia.

The correct type of tissue is needed to estimate biological age accurately, according to the study led by Abner Apsley, doctoral candidate in the Penn State Molecular, Cellular, and Integrative Biosciences Graduate Program, and his adviser, Idan Shalev, associate professor of biobehavioral health at Penn State. Their results were published in Aging Cell.

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