Emergency services are currently on scene at a fire on Stubbs Street, Auburn.
An exclusion zone has been declared.
Anyone who lives in the exclusion zone is asked to make themselves known to police.
Residents who live in the exclusion zone are asked to find alternative accommodation.
An assembly area has been set up at Dooley's Catholic Club, Lidcombe.
Parramatta Road is closed in both directions from St Hilliers Road to Hampstead Road, Auburn.
Diversions are in place.
The public is urged to avoid the area.
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