Berkeley Lab's Big Science Stories Of 2024

Berkeley Lab

This year, Lawrence Berkeley National Laboratory (Berkeley Lab) led research that pushes the boundaries of science and technology. From advancing our understanding of the universe to innovations in microelectronics, artificial intelligence, quantum science, and biomanufacturing, the lab's teams have achieved remarkable milestones across diverse fields.

To celebrate the end of the year, here's a roundup of some of our biggest stories that highlight the lab's impact on science, society, and the future.

Sayeef Salahuddin (left) and Nirmaan Shanker in the lab.

In the ongoing quest to make electronic devices smaller and more energy efficient, researchers want to bring energy storage directly onto microchips. This would reduce the losses when power is transported between various device components. To be effective, on-chip energy storage must be able to store a large amount of energy in a very small space and deliver it quickly when needed - requirements that can't be met with existing technologies. Addressing this challenge, scientists at Berkeley Lab have achieved record-high energy and power densities in microcapacitors made with engineered thin films of hafnium oxide and zirconium oxide, using materials and fabrication techniques already widespread in chip manufacturing.

This research was featured in IEEE Spectrum and The Cooldown.

Prabhat Kumar holding a computer with a simulation in front of a super computer.

The growing demand for artificial intelligence and the Internet of Things - the vast network of connected devices in everything from smart grids to smart homes - will require a new generation of microchips that are more energy efficient than current technologies. To meet this challenge, researchers developed FerroX, a new open-source, 3D simulation framework that could advance record-breaking energy efficiency in microelectronics. The modeling framework will help researchers understand microscopic phenomena and develop ultra-low-power microelectronics much faster and cheaper than current approaches, which rely on costly investments in material growth and device fabrication.

This research was featured in Scientific Computing World.

Illustration of a robot arm, vials, a laptop, and a beaker on a desk facing the window.

Researchers developed an automated workflow that could enable drug discovery and chemical reaction analysis in real time. Running from a desktop computer instead of in a lab, the automated workflow uses statistical analysis to identify new chemical reaction products within a few hours instead of days. The advance could help speed the discovery of new pharmaceutical drugs and accelerate the development of new chemical reactions.

This research was featured in Chem Europe.

An oil pump jack situated in a grassy field with a few bare trees.

Forgotten oil and gas wells - those not listed in state records and with no known operator - pose hazards to the environment. Researchers trained artificial intelligence to comb through the symbols on historical maps and find these potential "undocumented orphaned wells" (UOWs). In their study, researchers identified UOWs in California and Oklahoma, and the technique could be expanded to search for wells across the United States. The research is part of a multi-lab program to build inexpensive, flexible tools that states and tribes can use to find wells and prioritize them for plugging.

This research was featured in The Houston Chronicle and Popular Science.

Two gloved hands holding petri dishes of fungi.

Fungi are stepping into the spotlight as a promising sustainable, cruelty-free protein source for the future. A team led by Berkeley Lab developed a CRISPR-Cas9 toolkit to edit the genome of Aspergillus oryzae, or koji mold-famous for its use in sake and soy sauce. By enhancing its production of heme (for meat-like flavor) and ergothioneine (an antioxidant found only in fungi), the team turned the white mold into a red, meat-mimicking patty. The work is just the beginning of the journey to tap into fungal genomes to create new foods.

This research was featured in Newsweek, The New York Post, and KCBS.

A gene order map (created using GENESPACE) that compares genome assemblies among related plant species. The horizontal white lines represent chromosomes, and the colored braids that link them show conserved blocks of genes.

Modern hybrid sugarcane is one of the most harvested crops on the planet, used to make products including sugar, molasses, bioethanol, and bio-based materials. It also has one of the most complex genetic blueprints. Scientists mapped out sugarcane's DNA and created the first highly accurate reference genome for the plant - where they found a rare example of how genes confer disease resistance. Exploring sugarcane's genetic code could help researchers develop more resilient and productive crops, with implications for both sugar production and biofuels.

This research was featured in Earth.com.

A person testing electronics that are part of the experimental setup used for making qubits in silicon in a lab.

Quantum computers have the potential to solve complex problems in human health, drug discovery, and artificial intelligence millions of times faster than some of the world's fastest supercomputers. A network of quantum computers could advance these discoveries even faster. But before that can happen, the computer industry will need a reliable way to string together billions of qubits - or quantum bits - with atomic precision. To overcome this hurdle, researchers developed a method that uses a femtosecond laser to program the formation of telecom-band optical qubits in silicon for large-scale manufacturing. The technique could enable scalable quantum computers of the future by building on current silicon-based computing infrastructure.

This research was featured in Earth.com and Laser Focus World

Portrait of Bert de Jong, a person with short gray hair wearing a black jacket with arms crossed over chest, smiling.

Quantum technologies may still be in development, but these systems are evolving rapidly and existing prototypes are already making a big impact on science and industry. One of the major hubs of quantum R&D is the Quantum Systems Accelerator (QSA), led by Berkeley Lab. QSA is one of five National Quantum Information (NQI) Science Research Centers funded by DOE to develop technologies that can solve longstanding challenges in physics, chemistry, materials, and biology that can't be addressed with classical computers.

This research was featured in the Quantum Insider.

These images, generated by soft X-ray tomography performed by Berkeley Lab scientists, show the algae at different stages of cell division. UCYN-A, the nitrogen-fixing entity now considered an organelle, is cyan; the algal nucleus is depicted in blue, mitochondria are green, and chloroplasts are lilac.

After years of work, an international team that includes Berkeley Lab scientists found evidence that a once-independent nitrogen-fixing microbe has become a permanent resident within algae cells. The organelle is the fourth example in history of primary endosymbiosis - the process by which a prokaryotic cell is engulfed by a eukaryotic cell and evolves beyond symbiosis into an organelle.

One of the runner ups in Science's 2024 Breakthrough of the Year.

A teal cosmic map of the universe on a black background. Earth is at the center of this thin slice of the full map. There is a magnified section showing the underlying structure of matter in our universe.

One of the biggest mysteries in physics is dark energy, the unknown ingredient causing our universe to expand faster and faster. Researchers used the Dark Energy Spectroscopic Instrument (DESI) to create the largest 3D map of our universe to date, giving us world-leading measurements of dark energy and an unprecedented look at how the universe has expanded over 11 billion years. The experiment's first year of data provided tantalizing hints that dark energy might be evolving over time, but researchers will need more data to be sure. The DESI collaboration expects to publish its analysis of three years of data in 2025.

This research was featured in The New York Times, The Washington Post, Science, Nature, and Scientific American, and was named one of Time Magazine's Best Inventions of 2024.

Scientist Jacklyn Gates at the Berkeley Gas-filled Separator used to separate atoms of element 116, livermorium.

Berkeley Lab scientists are credited in the discovery of 16 of the 118 known elements. This year, researchers completed a crucial first step to potentially create a new element that would expand the periodic table. A team used the lab's 88-Inch Cyclotron to make known element 116 (livermorium) using a titanium beam for the first time, a breakthrough that enables the lab to try to make element 120. If discovered, element 120 would be the heaviest atom ever created and provide new insights into how the atomic nucleus behaves.

This research was featured in The Washington Post, Nature, Science, Scientific American, and Chemistry World.

Ethan Crumlin (far right) and Staff Scientist Jin Qian in the Advanced Light Source

In September, the Department of Energy announced the creation of the Energy Storage Research Alliance (ESRA), which is led by Argonne National Laboratory and co-led by Berkeley Lab and Pacific Northwest National Laboratory. ESRA provides the scientific underpinning to address battery challenges, including safety, high-energy density, and long-duration batteries made from inexpensive, abundant materials.

DOE's Efficient and Healthy Schools Program recognized 13 school district honorees. Berkeley Lab has provided technical support to the Efficient and Healthy Schools Program since its launch in 2021. The team includes staff from Berkeley Lab's Energy Technologies Area who help design and administer this recognition program.

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