Researchers at the University of Plymouth are leading an innovative initiative to advance the study of meningiomas in NF2-related schwannomatosis (NF2-SWN).
Meningiomas, often linked to the loss of the NF2 gene, are a hallmark of NF2-SWN and can severely impact patients' lives despite being typically non-malignant.
Through this new project, researchers will address two critical gaps in meningioma research - the development of effective therapies that improve patient outcomes, and the inability to study the interactions between human immune cells and meningioma tumour cells in living systems before advancing new therapies to clinical trials.
To do this, scientists at the University's
Brain Tumour Research Centre of Excellence - with funding from the Children's Tumor Foundation (CTF) - will develop a humanised meningioma model for NF2-SWN, which will enable researchers worldwide to study these complex interactions and accelerate the development of new therapies.
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