With the continuous development of nanotechnology, more artificial chiral nanomaterials have been constructed. As one of the most representative optical properties of these chiral nanomaterials, CD is a powerful sensing technology. Compared with other analytical methods, CD signal has higher sensitivity, but it cannot achieve in-situ imaging in vivo. Scientists have managed to prepare chiral nanocomposites with more diverse biological functional properties to compensate for this shortcoming. However, some chiral nanocomposites assembled by electrostatic adsorption or other methods are easily dissociated and destroyed in complex physiological environments, resulting in performance deviations. In addition, it is difficult for some nanocomposites to distinguish interferences with properties similar to the analyte, resulting in poor detection selectivity. Therefore, it is still a challenging task to develop chiral composite nanomaterials with stable structure and excellent properties to meet the needs of biomedical diagnosis and detection.
In a new paper published in Light: Science & Application, a team of scientists, led by Professor Geyu Lu from State Key Laboratory of Integrated Optoelectronics, College of Electronic Science and Engineering, Jilin University, China and co-workers have developed a UCNPs/Cux
