City of Hope Shares Promising Stem Cell and Blood Cancer Data at ASCO 2024

LOS ANGELES — World-renowned physicians and researchers from City of Hope^®, one of the largest cancer research and treatment organizations in the United States, will present new findings and offer expert perspectives on leading-edge cancer research and treatment development at the ASCO Annual Meeting 2024, which will take place in Chicago from May 31 to June 4.

In total, City of Hope experts will present at 64 sessions, including oral abstracts, rapid oral abstracts, clinical science symposiums and education sessions.

ORAL AND RAPID ORAL ABSTRACT SESSIONS

• "Overall survival (OS) of phase 3 CodeBreaK 300 study of sotorasib plus panitumumab (soto+pani) versus investigator's choice of therapy for KRAS G12C-mutated metastatic colorectal cancer (mCRC)"

Session LBA 3510 presenting Monday, June 3, from 1:21 to 1:27 p.m. CT

Session title: Gastrointestinal Cancer—Colorectal and Anal

Presenter: Marwan G. Fakih, M.D., City of Hope professor, Department of Medical Oncology & Therapeutics Research

• "Post-transplant cyclophosphamide-based graft-versus-host disease prophylaxis following mismatched unrelated donor peripheral blood stem cell (PBSC) transplantation"

Session 6503 presenting on Friday, May 31, from 3:45 to 3:57 p.m. CT

Session title: Hematologic Malignancies—Leukemia, Myelodysplastic Syndromes, and Allotransplant

Presenter: Monzr M. Al Malki, M.D., City of Hope associate professor, Division of Leukemia, Department of Hematology & Hematopoietic Cell Transplantation

• "Glofitamab monotherapy in patients with heavily pretreated relapsed/refractory (R/R) mantle cell lymphoma (MCL): Updated analysis from a phase I/II study"

Session 7008 presenting on Saturday, June 1, from 5:24 to 5:36 p.m. CT

Session title: Hematologic Malignancies—Lymphoma and Chronic Lymphocytic Leukemia

Presenter: Tycel Phillips, M.D., City of Hope associate professor, Division of Lymphoma, Department of Hematology & Hematopoietic Cell Transplantation

• "Preliminary safety, pharmacokinetics and clinical activity of DFF332, an oral HIF2α inhibitor, as monotherapy in a phase 1 dose escalation study in patients with advanced clear cell renal cell carcinoma"

Session 4513 presenting Saturday, June 1, from 8:30 to 8:36 a.m. CT

Session title: Genitourinary Cancer—Kidney and Bladder

Presenter: Sumanta Kumar Pal, M.D., FASCO, City of Hope professor, Department of Medical Oncology & Therapeutics Research

CLINICAL SCIENCE SYMPOSIUMS

• "Geriatric assessment-directed supportive care intervention (GAIN-S)-implementation via telehealth in a lower-resourced community"

Session 1510 presenting Saturday, June 1, from 1:39 to 1:51 p.m. CT

Session title: Patient-Centered Care for Older Adults With Cancer

Presenter: Tanyanika Phillips, M.D., M.P.H., City of Hope assistant clinical professor, Department of Medical Oncology & Therapeutics Research

Senior author: William Dale, M.D., Ph.D., FASCO, City of Hope professor, Department of Supportive Care Medicine

• "Quality of life for older patients with metastatic cancer in Brazil: A telehealth-based geriatric assessment and supportive care intervention (GAIN-S)"

Session 1514 presenting Sunday, June 2, from 11:54 a.m. to 12:06 p.m. CT

Presenter: Cristiane Decat Bergerot, Ph.D.

Senior author: William Dale, M.D., Ph.D., FASCO, City of Hope professor, Department of Supportive Care Medicine

POSTER ABSTRACT SESSION

• "A phase I/II trial of palbociclib, pembrolizumab, and endocrine therapy for patients with HR+/HER2- locally advanced or metastatic breast cancer (MBC): Clinical outcomes and stool microbial profiling"*

Session 1038 on Sunday, June 2, from 9 a.m. to noon CT

Session Title: Breast Cancer—Metastatic

Presenter: Alexis LeVee, M.D., City of Hope Hematology & Medical Oncology Chief Fellow

* Conquer Cancer, the ASCO Foundation, awarded LeVee a 2024 ASCO Annual Meeting Merit Award, which supports students and trainees who are first authors on abstracts selected for presentation.

At the meeting, ASCO will recognize researchers who have reshaped cancer care. City of Hope's William Dale, M.D., Ph.D., FASCO, is the recipient of this year's B.J. Kennedy Geriatric Oncology Award, which honors geriatric oncologists who have demonstrated outstanding leadership and achievement in the field of geriatric oncology. Dale is the first non-oncologist recipient in the history of the award. Of note, Dale is first author of ASCO's recent cancer and aging guideline update.

• Online on-demand award lecture on Friday, May 31, from 1 to 1:45 p.m. CT

Presenter: William Dale, the George Tsai Family Chair in Geriatric Oncology and vice chair for academic affairs in the Department of Supportive Care Medicine at City of Hope

EDUCATION SESSIONS

• "Evidence Evaluating Cannabis' Efficacy Across the Cancer Care Continuum"

Monday, June 3, from 8:30 to 8:45 a.m. CT

Session title: Evidence-Based Integrative Oncology: Guideline Insights for Comprehensive Care

Presenter: Richard T. Lee, M.D., FASCO, City of Hope clinical professor, Supportive and Integrative Medicine Program; Cherng Family Director's Chair for the Center for Integrative Oncology

• "Tissue-Based Molecular Testing and the Role of Artificial Intelligence"

Monday, June 3, from 10 to 10:15 a.m. CT

Session title: Should I Order the Test? Expanding the Array of Emerging Diagnostics in Breast Cancer

Presenter: Daniel Schmolze, M.D., City of Hope associate clinical professor, Department of Pathology

• "What Is Variant Histology Renal Cell Cancer and What Are the Available Treatment Options?"

Monday, June 3, from 3:15 to 3:30 p.m. CT

Session title: Managing Variant Histologies in Urothelial and Renal Cell Cancers

Presenter: Sumanta Kumar Pal, M.D., FASCO, City of Hope professor, Department of Medical Oncology & Therapeutics Research