https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2024.0036
Announcing a new article publication for Cardiovascular Innovations and Applications journal. Acute morphological changes in de novo coronary lesions after drug-coated balloon (DCB) angioplasty can affect endothelial mechanics and consequently clinical outcomes.
Angiography-based computational modeling has been validated to assess endothelial dynamic strain (EDS) in coronary arteries in vivo. The EDS was calculated on the basis of pre- and post-DCB angiography. Parameters of quantitative coronary angiography and EDS were quantified at cross-sections in the treated segments. A total of 336 and 348 lesion cross-sections were included in the small/large vessel groups, respectively. The acute lumen gain after DCB was significantly higher in large than small vessels (relative changes: 21.3% [17.4%, 25.1%] vs. 7.4% [4.8%, 10.1%], P
Further study is required to examine the clinical value of EDS in predicting cardiac events after DCB treatment.
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Lei Xu, Zhouhao Tang and He Zou et al. Angiography-Based Computational Modeling for In Vivo Assessment of Endothelial Dynamic Strain in Coronary Arteries with De Novo Lesions: Comparison of Treatment Effects of Drug-Coated Balloons Between Small and Large Arteries. CVIA. 2024. Vol. 9(1). DOI: 10.15212/CVIA.2024.0036
