Factors Impacting Racial Disparities in Colorectal Cancer

JAMA Network

About The Study: This single-center cohort study identified substantial overall survival disparity and differing frequencies of driver gene variations by race and ethnicity. Socioeconomic status had the largest contribution but accounted for less than one-third of the disparity, with substantial contribution from tumor molecular features. Further study of the associations of genetic ancestry and the molecular pathogenesis of colorectal cancer with chemotherapy response is needed.

Corresponding Author: To contact the corresponding author, John Paul Shen, MD, email [email protected].

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(doi:10.1001/jamaoncol.2024.3666)

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