Familial Risk of Depression Impairs Cognitive Function

JAMA Network

About The Study: Depression in prior generations was associated with lower cognitive performance in offspring, whether assessed by family history or genetic data. There are opportunities to generate hypotheses about how this arises through genetic and environmental determinants, moderators of brain development and brain aging, and potentially modifiable social and lifestyle factors across the life span.

Authors: Breda Cullen, Ph.D., of the University of Glasgow in Glasgow, United Kingdom, is the corresponding author.

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(10.1001/jamapsychiatry.2023.0716)

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