Homicide Squad detectives are investigating the circumstances surrounding the death of a man in Wyndham Vale this evening.
Emergency services were called to a bus stop near Haines Drive following reports of an altercation about 8pm.
On police arrival, a man was located with wounds consistent with a stabbing.
Medical treatment was provided, but he died at the scene.
The man is yet to be formally identified.
Two offenders then fled the scene before police arrived, heading along Vaughn Street.
A crime scene has been established while detectives investigate to determine what occurred.
Anyone who witnessed the incident, with dashcam/CCTV footage or information is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au.