Homicide Squad detectives are investigating the circumstances surrounding the death of a man in St Kilda last night.
Emergency services were called to reports of a house fire on Chapel Street about 8.40pm.
Responding firefighters located a critically injured man, who is yet to be formally identified, inside the property.
He was treated but died at the scene.
The exact circumstances surrounding the death, as well as the fire at the property, are yet to be determined and the matter is being treated as suspicious.
A crime scene has been established and an arson chemist will assess the scene.
Anyone who witnessed anything suspicious, has CCTV, dashcam footage or any other information that could assist investigators is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au