Incidence of viral rebound after treatment with nirmatrelvir-ritonavir and molnupiravir

JAMA Network

About The Study: In this study of 12,600 adults in Hong Kong with COVID-19 who were hospitalized, viral rebound was uncommon in patients taking molnupiravir or nirmatrelvir-ritonavir and was not associated with increased risk of mortality. Given these findings, novel oral antivirals should be considered as a treatment for more patients with COVID-19 in the early phase of the infection.

Authors: Grace Chung-Yan Lui, M.D., of the Chinese University of Hong Kong, is the corresponding author.

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(doi:10.1001/jamanetworkopen.2022.45086)

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