Major Collision Investigation Unit detectives are investigating a fatal collision in Molesworth yesterday afternoon.
Emergency services were called to reports that a white Nissan Navara utility collided with a white Isuzu utility on the Goulburn Valley Highway, east of Molesworth, on Thursday, 31 October about 2pm.
The Isuzu left the road and crashed into a tree.
The male driver, and sole occupant, of the Isuzu utility was airlifted to hospital with life-threatening injuries but later died in hospital.
The driver of the Nissan Navara utility, a 25-year-old Wonga Park man was taken to hospital with minor-injuries and is currently under police guard.
The exact circumstances surrounding the collision are yet to be determined and investigations remain ongoing.
Anyone who witnessed the incident or who has footage, is urged to contact Crime Stoppers on 1800 333 000 or visit www.crimestoppersvic.com.au