Maths' Unexpected Role in Blood Clot Studies

Mathematics can help predict thrombosis. Mathematician Mark Alber has developed models that even aid in suggesting treatments. In the Kloosterman lecture on 27 June, he will explain how this works.

The mathematical models of Professor Mark Alber and his team can help us by suggesting treatment strategies for patients with thrombosis. The have created so-called digital twins. These twins serve as virtual representations of real people, used for simulation, testing and monitoring. Alber: 'Together with the University of Pennsylvania School of Medicine, our group has introduced new twins specifically for modelling clotting in individual patients. These mathematical models can be calibrated for suggesting patient specific treatment strategies.'

Alber highlights the importance of this work: 'Thrombosis is one of the leading causes of death worldwide. Evaluating and predicting the mechanical stability of a blood clots under various conditions such as deformation, contraction and different flows, is necessary for evaluation of the risk of thrombosis.'

More about the Kloosterman chair

Each year, a distinguished mathematician is appointed as a visiting professor at the Mathematical Institute. This chair is named after Hendrik Douwe Kloosterman (1900-1968). Kloosterman, who lectured in Leiden from 1930 and became a full professor in 1947, is renowned for his work in analytic number theory, particularly for 'Kloosterman sums'

Why you should join the lecture

Alber is currently visiting the Mathematical Institute (MI) on a four-month sabbatical with a prestigious Fulbright US Scholar Fellowship. He is hosted by professors Roeland Merks and Arjen Doelman.

Mark Alber

Merks is delighted that Alber will be part of the MI for the coming months: 'Mark is a world-renowned expert in Mathematical Biology with a stellar track-record in modelling multicellular systems. He brings along years of experience.'

Doelman confirms this heartily: 'Mark gives great presentations and is exceptionally strong in communicating with colleagues in fields outside mathematics. He shows how powerful mathematics can be in the context of other scientific areas. Therefore, his talk will relevant and interesting for many colleagues in our faculty.'

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