Microprobe with Ultrahigh Sensitivity Detects Molecular Fingerprints

Researchers working with Lan Yang, the Edwin H. & Florence G. Skinner Professor at the McKelvey School of Engineering at Washington University in St. Louis, have developed a scanning whispering-gallery-mode (WGM) microprobe. This novel device represents a shift in the world of microsensors, offering a remarkable solution to the sensitivity-detection area trade-off conundrum. The findings were published Oct. 5 in Light: Science & Applications.

"Akin to placing a contact lens on a tested sample, the WGM microprobe not only focuses light into a smaller spatial spot but also 'converges' it in the time domain, trapping light in a microsphere smaller than the diameter of a single strand of hair," said Wenbo Mao, first author on the paper and a graduate student in Yang's lab. "This enables light to interact with target molecules thousands of times, greatly boosting the signal."

/Public Release. This material from the originating organization/author(s) might be of the point-in-time nature, and edited for clarity, style and length. Mirage.News does not take institutional positions or sides, and all views, positions, and conclusions expressed herein are solely those of the author(s).View in full here.