Homicide Squad detectives have arrested six men as part of their investigation into a fatal shooting in Kalkallo in September.
Six search warrants were executed in Mickleham, Keilor, Craigieburn and Wallan today.
A 24-year-old Mickleham man has been charged with one count of murder and has been remanded to appear at the Melbourne Magistrates' Court on 11 October.
A 25-year-old Wallan man and a 19-year-old Craigieburn man have been charged with home invasion and have been remanded to appear at the Melbourne Magistrates' Court on 11 October.
A 31-year-old Wallan man remains in custody and is yet to be interviewed at this stage.
A 22-year-old Keilor woman and a 22-year-old Wallan man have been released pending further enquiries.
The charges follow an incident in Kalkallo on September 21 where a 22-year-old Kalkallo man was fatally shot.
Emergency services were called to an address on Oodgeroo Road shortly after 4.15am following reports a man had been injured during an altercation at the address.
When police attended, they located the 22-year-old Kalkallo man deceased at the property.
Investigators believe the shooting was a targeted incident and the parties involved were known to each other.