New Strategies Emerge for Rare Bladder Disease Treatment

Society for Neuroscience

Despite its increasing prevalence, a painful condition called bladder pain syndrome, or interstitial cystitis, remains understudied with limited treatment options. In a new eNeuro paper, Min-Zhi Su and colleagues, from Sun Yat Sen University, used a rat model of bladder pain syndrome to explore if electroacupuncture can alleviate pain and improve bladder function. Electroacupuncture nerve stimulation therapy has shown promise in treating conditions like Huntington's disease and Amyotrophic Lateral Sclerosis, but researchers have not explored its utility in this context. The researchers discovered that this kind of therapy can reduce neuropathic pain, promote urinary function, and decrease neuroinflammation. They also discovered a mechanism through which electroacupuncture may work. According to the authors, these findings suggest that electroacupuncture may be a promising treatment strategy for bladder pain syndrome, though future work in more advanced animal models—and eventually in people—is needed.

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