Police are appealing for information, as part of Missing Persons Week, into the disappearance of Rhyanwen Horne nee McConnochie, more than 48 years ago.
Rhyanwen Horne nee McConnochie was last seen at the Shortland Clinic, now demolished, on the corner of Ordnance and Watt Street, Newcastle, about 8.15pm on Saturday 1 February 1975.
When she could not be located, officers attached to Newcastle City Police District were notified and commenced inquiries into her whereabouts.
Rhyanwen was 24 years old when she was reported missing. She would now be aged 73.
Newcastle City Police District Commander, Superintendent Kylie Endemi, said there's no piece of information too small for police to consider as part of the investigation.
"Please, If you know anything – even if you believe it's minor or insignificant – our investigators would love to hear from you," Supt Endemi said.
Rhyanwen's sister, Kathryn McConnochie, said that after 48 years without information, the family needs answers.
"It has been far too long without knowing what has happened to my sister," Ms McConnochie said.
"If anyone has any information about her, either before or after she went missing, no matter how minor it may seem, please come forward with it."
At the time of her disappearance, Rhyanwen was described as being of Caucasian appearance, fair complexion, 170cm tall, with slight build, very long wavy brown hair and grey-green eyes.
Anyone who may hold information that can assist investigators is urged to contact Crime Stoppers on 1800 333 000.
Anyone with information about this incident is urged to contact Crime Stoppers: 1800 333 000 or https://nsw.crimestoppers.com.au. Information is treated in strict confidence. The public is reminded not to report information via NSW Police social media pages.