Reston, VA (April 25, 2025)—New research has been published ahead-of-print by The Journal of Nuclear Medicine (JNM). JNM is published by the Society of Nuclear Medicine and Molecular Imaging, an international scientific and medical organization dedicated to advancing nuclear medicine, molecular imaging, and theranostics—precision medicine that allows diagnosis and treatment to be tailored to individual patients in order to achieve the best possible outcomes.
Summaries of the newly published research articles are provided below.
Personalizing Treatment for Neuroendocrine Tumors
Researchers studied how a targeted therapy behaves in the body over time, using advanced imaging and AI to track dose patterns in tumors and kidneys. The findings reveal important differences based on tumor type and kidney health, paving the way for more tailored treatment strategies in the future.
Sharper Scans with Lower Doses
Can cancer scans be just as effective with far less tracer activity? This study tested a new PET/CT scanner that delivers clear images using ultralow doses of tracer. Results show promise for accurate imaging with dramatically reduced exposure—especially important for sensitive patients like children or those needing repeated scans.
A Promising New Scan for Parathyroid Disorders
Researchers explored a new PET/CT imaging method using 18F-flurpiridaz to locate overactive parathyroid glands in patients with primary hyperparathyroidism. The scan successfully identified abnormal glands in most patients, especially during early imaging, suggesting it could become a powerful tool alongside traditional tests for diagnosing and treating this condition.
Tracking Prostate Cancer Progress with Smarter Imaging
Researchers studied how well a specific scan—LuPSMA SPECT/CT—can predict outcomes in advanced prostate cancer patients undergoing targeted therapy. When combined with PSA levels, this imaging method offered similar insight as more advanced scans, suggesting a simpler, effective way to monitor treatment and guide decisions in clinical care.
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