Major Collision Investigation Unit detectives are investigating a fatal collision in Mannibadar this morning.
It is believed a car and motorcycle collided at the intersection of Skipton Rokewood Drive and Linton-Mannibadar Road about 9am.
The motorcyclist, who is yet to be formally identified, died at the scene.
The driver of the vehicle, a 35-year-old Alfredton man, stopped at the scene and is currently assisting police with their enquiries.
The exact circumstances surrounding the collision are yet to be determined and investigations remain ongoing.
Motorists are advised to avoid the area with the roads expected to be closed for several hours.
Anyone who witnessed the incident, has CCTV, dashcam footage or any other information that could assist police is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au