Major Collision Investigation Unit detectives are investigating the circumstances surrounding a fatal collision in Princetown this afternoon.
Emergency services were called to the Great Ocean Road after two vehicles collided head on about 3.40pm.
The the driver of the first vehicle was taken to hospital with non-life-threatening injuries.
Their yet-to-be formally identified passenger died at the scene.
A passenger of the second vehicle, who is yet-to-be formally identified, also died at the scene.
The driver and another passenger of the second vehicle were taken to hospital with serious injuries.
Anyone who witnessed the crash or with footage is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au.