Homicide Squad detectives are investigating after a man was fatally stabbed in Thomastown last night.
Police were called to a Victoria Drive address about 8.40pm on 11 July following reports a man had been stabbed.
Medical assistance was provided, however the 36-year-old Doreen man died at the scene.
Police arrested a 45-year-old Glenroy man at the scene and he remains in custody.
Detectives are still searching for a second person in relation to the incident.
At this early stage in the investigation, the incident appears to be a targeted attack.
Detectives are keen to speak to anyone in the area who may have CCTV or dash-cam footage.
Anyone with information is urged to contact Crime Stoppers on 1800 333 000 or make a confidential report online at www.crimestoppersvic.com.au