Police have arrested a man following a three-vehicle collision in Noble Park late last night.
It is believed that a black Mercedes, travelling northbound on the Princes Freeway, collided with a white Fiat and a black MG about 10pm.
A passenger from the Fiat, a 34-year-old Clayton South woman, was taken to hospital with serious injuries.
The drivers of both the Fiat and the MG were taken to hospital for treatment.
The driver of the Mercedes was arrested at the scene and taken to hospital for treatment, where he remains under police guard.
The 19-year-old Noble Park man will be interviewed by police when released from hospital.
The investigation into the circumstances surrounding the three-vehicle collision remains ongoing.
Anyone who witnessed the incident, has CCTV, dashcam footage or any other information that could assist police is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au