Major Collision Investigation Unit detectives have charged a man following a fatal collision in Pine Lodge on Friday, 19 April.
It is alleged a Toyota Camry, a Toyota Aurion and a Mazda wagon collided at the intersection of New Dookie and Boundary Road about 6.20pm.
The driver of the Camry, a 30-year-old Kialla man, sustained serious injuries and was taken to hospital for treatment.
One of his passengers, a 16-year-old Lemnos girl, sustained serious injuries and later died in hospital.
His second passenger, a 32-year-old Lemnos man, also sustained serious injuries while the third passenger, an 18-year-old Tarneit woman, was not injured.
The other drivers and a male passenger involved in the collision sustained non-life-threatening injuries and were taken to hospital for treatment.
The 30-year-old driver of the Camry has been charged with dangerous driving causing death and dangerous driving causing serious injury.
He has been bailed to appear at Shepparton Magistrates' Court on 6 May.