Police are concentrating their search in the Jamieson area today following a possible sighting of Guy and Susan Beesley's car on Monday afternoon.
Police have received information about a possible sighting of the couple's car on Monday about 4.30pm on the Jamison Licola Road.
Police are continuing their serach in the high country after the pair were last seen leaving an address in Mansfield at 3.25pm on Monday 28 October, bound for their home in Willung.
It is believed they were travelling in their white 2016 Land Rover Discovery Wagon, registered AJT 166.
They last made contact with family about 8.30am on Monday to advise they were intending to return home via Dinner Plain, however they have not returned home and have not made contact with family since.
Murrindindi Senior Sergeant Mark Hesse said a Land Rover Discovery was sighted facing towards Licola, about 28km from Jamison.
"In particular, we are appealing for two trail bike riders who were seen on the opposite side of the road to the Land Rover to come forward," he said.
"The two riders on stationary trail bikes were seen facing the opposite direction to the Land Rover.
"We would like to speak to these two riders to ascertain if they saw Guy and Susan with this vehicle."
Guy is Caucasian and described as about 175cm tall with a medium build, is bald and has blue eyes.
He was last seen wearing dark coloured clothing.
Susan is Caucasian and described as about 165cm tall with a medium build, shoulder length straight blonde hair with a front fringe and hazel eyes.
She was last seen wearing a rust coloured t-shirt, skinny jeans and a black zip-up jacket with a grey quilted collar.
Police have released an image of the pair as well as their vehicle in the hope someone recognises them and can provide information on their whereabouts.
Anyone who sights Guy and Susan or their vehicle, or who knows of their whereabouts is urged to contact Benalla Police Station on 03 5760 0200.