Major Collision Investigation Unit detectives are investigating a collision in Hampton last night.
It is understood a Mazda Tribute wagon and a Yamaha motorbike collided in the intersection of Beach Road and Orlando Street about 8.30pm.
The rider, a 33-year-old man from Somerville, was transported to hospital with life-threatening-injuries and he is now in a stable condition.
The driver of the Mazda, a 21-year-old woman from Brighton East, stopped at the scene and is assisting police with their enquiries.
Anyone who witnessed the collision, has dashcam/CCTV footage or information is urged to contact Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppersvic.com.au
Quotes attributable to Detective Sergeant Lee Barton, Major Collision Investigation Unit:
"Victoria Police will take this opportunity to address road user behaviour and attitudes that can contribute to serious collisions. Slow down and take a moment when travelling.
"We have seen a spike in motorcycle incidents this year already."