Major Collision Investigation Unit detectives have charged a man following a quadruple fatality in Pine Lodge early this month.
A car and ute collided on Pine Lodge North Road, near Cosgrove-Lemnos Road, about 4.45pm on 4 January.
The ute driver, a 29-year-old Nathalia man, was taken to hospital with minor injuries.
There were five people in the car that collided with the ute, struck a road sign and came to rest in a nearby paddock.
Four of the five occupants from the car died at the scene.
The driver of the car, a 41-year-old Shepparton man, was taken to hospital with non-life threatening injuries where he remains under police guard.
He has been charged with four counts of dangerous driving causing death and remanded to appear in Melbourne Magistrates' Court on 8 June.