Biofilms have long been recognized in nature and may be found adhering to a variety of surfaces, including rocks in streams (slime), mammalian teeth, roots of plants and even in water pipes. Biofilms may be the most adaptable microbial feature in nature. However, when the associated microbes are pathogenic, this ability to aggregate into biofilms becomes a significant virulence factor. In fact, the vast majority of human infections are actually biofilm mediated
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