PHILADELPHIA, PA – November 18, 2024 – Opertech Bio, Inc., a leading innovator in taste assessment, today announced the publication of a research article in which the TāStation® rapid throughput taste evaluation system was used to resolve a central question about sweet taste perception.
It has been well established that sweeteners impart their taste by activating the TAS1R2/TAS1R3 "sweet taste receptor" in the tongue. A second signaling pathway involving the activity of glucose transporters, operating independently of the receptor, recently has been proposed for metabolizable caloric sweeteners. In a powerful demonstration of the analytical capacity of the TāStation® in combination with a pharmacological experimental approach, all sweet taste signaling was shown to occur exclusively through the receptor with no contribution by a glucose transporter mechanism.
