Major Collision Investigation Unit detectives are investigating the circumstances surrounding the death of a woman in Kangaroo Ground tonight (Friday 5 June).
Investigators have been told a white four-wheel drive crossed onto the wrong side of the road and struck a small Toyota hatch on Kangaroo Ground - Warrandyte Road about 3.20pm.
A 19-year-old Croydon woman who was the passenger in the Toyota hatch was airlifted to hospital with life threatening injuries but unfortunately later died.
A 19-year-old Croydon man who was driving the Toyota hatch was also transported to hospital and remains in a serious condition.
A 58-year-old Rhyll woman who was driving the four-wheel drive was transported to hospital for minor injuries.
She will be interviewed by investigators at a later date.
Anyone with dashcam footage or information that could assist police with enquiries is urged to Crime Stoppers on 1800 333 000 or submit a confidential report online at www.crimestoppers.com.au