Zerlasiran: RNA Targets Lipoprotein

JAMA Network

About The Study: Zerlasiran, a small-interfering RNA targeting hepatic synthesis of apolipoprotein(a), was well-tolerated and reduced time-averaged lipoprotein(a) concentration by more than 80% during 36 weeks of treatment in patients with atherosclerotic cardiovascular disease.

Corresponding Author: To contact the corresponding author, Steven E. Nissen, MD, email [email protected].

To access the embargoed study: Visit our For The Media website at this link https://media.jamanetwork.com/

(doi:10.1001/jama.2024.21957)

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